Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590600 | 0.98 | CYP3A4 (0.47) | CYP3A4CYP2A6MEN1KMT2AIDO1 | |
| Pyridine SCHEMBL27784037 | 0.76 | CYP3A4 (0.38) | CYP3A4CYP2A6MEN1KMT2ATSHR | |
| SCHEMBL28061806 | 0.74 | CYP3A4 (0.50) | CYP3A4CYP2A6MEN1KMT2AIDO1 | |
| SCHEMBL141173 | 0.73 | POLB (0.41) | CYP3A4MEN1KMT2ATSHRLMNA | |
| SCHEMBL27457703 | 0.72 | MEN1 (0.60) | CYP3A4CYP2A6MEN1KMT2AIDO1 | |
| SCHEMBL27656935 | 0.72 | SMN1; SMN2 (0.40) | CYP3A4MEN1KMT2ATSHRLMNA | |
| SCHEMBL8724216 | 0.71 | CYP11B1 (0.42) | CYP3A4CYP2A6MEN1KMT2AIDO1 | |
| SCHEMBL3787426 | 0.69 | LMNA (0.47) | CYP3A4CYP2A6MEN1KMT2AIDO1 | |
| SCHEMBL7007434 | 0.68 | MEN1 (0.56) | CYP3A4MEN1KMT2AIDO1ALOX15 | |
| SCHEMBL8724044 | 0.68 | CYP11B1 (0.39) | CYP3A4CYP2A6MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271290-A | Continuous flow preparation method of trithio s-triazine compound | 上海沃凯生物技术有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-114799200-A | Preparation method of high-dispersibility silver powder | 中科铜都粉体新材料股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| JP-55105682-A | — | — | None | — | — | JP | disclosed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118271290-A | Continuous flow preparation method of trithio s-triazine compound | 上海沃凯生物技术有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114799200-B | Preparation method of high-dispersity silver powder | 中科铜都粉体新材料股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-110250261-B | Compound preservation method for kiwi fruits | 南阳师范学院 | 2022-10-14 | — | — | CN | disclosed |
| CN-114799200-A | Preparation method of high-dispersibility silver powder | 中科铜都粉体新材料股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-110483506-B | Novel method for constructing 2- (2-thienyl) imidazole [1,2-a ] pyridine-3-aldehyde by using DMF as formylation reagent | 桂林理工大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-108912182-B | Aluminum and chromium ion multichannel response probe and synthetic method and application thereof | 内蒙古工业大学 | 2020-11-20 | — | — | CN | disclosed |
| CN-110483506-A | Using DMF as formylation reagent construct 2-(2- thienyl) imidazoles [1,2-a] pyridine -3- aldehyde new method | UNIV GUILIN TECHNOLOGY | 2019-11-22 | — | — | CN | disclosed |
| US-6235766-B1 | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-05-22 | — | — | US | disclosed |
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-4810800-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-03-07 | — | — | US | disclosed |
| CN-87103323-A | The method for preparing new Dopamine HCL, hydroxylase inhibitors | — | 1988-02-03 | — | — | CN | disclosed |
| EP-0244803-A2 | Novel dopamine beta hydroxylase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-11-11 | — | — | EP | disclosed |
| JP-S55105682-A | PRODUCTION OF THIENYLIMIDAZOLES | YOSHITOMI PHARMACEUT IND LTD | 1980-08-13 | — | — | JP | disclosed |