Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460079 | 0.88 | MGLL (0.57) | MGLLCCR3CA12CA1CA2 | |
| SCHEMBL21078088 | 0.85 | KMT2A (0.61) | MGLLAKR1C3HDAC3HDAC4HDAC1 | |
| SCHEMBL7320522 | 0.84 | HDAC3 (0.64) | MGLLAKR1C3HDAC3HDAC4HDAC1 | |
| SCHEMBL25442214 | 0.84 | ALDH1A1 (0.61) | MGLLAKR1C3HDAC3HDAC4HDAC1 | |
| SCHEMBL23884836 | 0.82 | AKR1C3 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20632698 | 0.81 | ALDH1A1 (0.52) | AKR1C3L3MBTL3L3MBTL1 | |
| SCHEMBL6339480 | 0.81 | L3MBTL3 (0.56) | MGLLCCR3CA12CA1CA2 | |
| SCHEMBL3001302 | 0.79 | MGLL (0.61) | MGLLCA12CA1CA2CA7 | |
| SCHEMBL31267062 | 0.79 | MGLL (0.61) | MGLLCA12CA1CA2CA7 | |
| SCHEMBL13575475 | 0.79 | MGLL (0.61) | MGLLCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079719-A1 | PYRIMIDINE KINASE INHIBITORS | GENENTECH, INC. (US) | 2008-07-03 | — | — | WO | disclosed |