Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412460 | 0.85 | KDM4E (0.46) | HPGDKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL26846962 | 0.81 | MAPK1 (0.52) | HPGDKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL1412550 | 0.80 | KDM4E (0.47) | HPGDKDM4EALDH1A1USP2MAPK1 | |
| SCHEMBL1412598 | 0.79 | KDM4E (0.42) | HPGDKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL20531569 | 0.79 | GAA (0.45) | KDM4EALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL9915129 | 0.76 | KDM4E (0.46) | HPGDKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL26034982 | 0.76 | KDM4E (0.46) | HPGDKDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4785326 | 0.76 | CYP19A1 (0.57) | HPGDKDM4EALDH1A1PTGER4SMN1; SMN2 | |
| SCHEMBL1412609 | 0.76 | LMNA (0.45) | HPGDKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL1412486 | 0.76 | UCHL1 (0.52) | HPGDKDM4EALDH1A1PTGER4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991542-B1 | HERBICIDAL ISOXAZOLINE COMPOUNDS | SYNGENTA LTD (GB) | 2011-03-16 | — | — | EP | disclosed |
| US-20100004128-A1 | HERBICIDAL ISOXAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-07 | — | — | US | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1991542-A1 | HERBICIDAL ISOXAZOLINE COMPOUNDS | Syngenta Limited (GB) | 2008-11-19 | — | — | EP | disclosed |
| EP-1965644-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007096576-A1 | HERBICIDAL ISOXAZOLINE COMPOUNDS | SYNGENTA LIMITED (GB) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004128-A1 | HERBICIDAL ISOXAZOLINE COMPOUNDS | CYP4X1, RDX, HAX1 | HPGD 1172/4885KDM4E 2140/4885ALDH1A1 328/4885 |
| US-20090042726-A1 | Novel Herbicides | DDT, CBR3, CBR1 | HPGD 1388/4885KDM4E 1271/4885ALDH1A1 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.