SCHEMBL1412427

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28728827	0.82	PDE4D (0.52)	KDM4EMAPTPOLBKMT2APDE4D
	SCHEMBL841773	0.77	PDE4D (0.52)	KDM4EMAPTPOLBKMT2APDE4D
	SCHEMBL24334811	0.75	KDM4E (0.46)	KDM4EMAPTPOLBKMT2ANPSR1
	SCHEMBL1412585	0.74	PDE4D (0.44)	KDM4EMAPTPOLBKMT2APDE4D
	SCHEMBL31332897	0.74	L3MBTL1 (0.46)	KDM4EMAPTPOLBKMT2APDE4D
	SCHEMBL19924873	0.73	MAPT (0.56)	KDM4EMAPTKMT2ANPSR1ALDH1A1
	SCHEMBL30468618	0.73	MAPT (0.56)	KDM4EMAPTKMT2ANPSR1ALDH1A1
	SCHEMBL2371687	0.73	KDM4E (0.55)	KDM4EMAPTKMT2ANPSR1ALDH1A1
	SCHEMBL20471481	0.72	KDM4E (0.74)	KDM4EMAPTPOLBKMT2APDE4D
	SCHEMBL13365026	0.72	KDM4E (0.50)	KDM4EMAPTPOLBKMT2APDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.