Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127679 | 1.00 | DGAT1 (0.61) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL14127680 | 1.00 | DGAT1 (0.61) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL14235872 | 0.88 | DGAT1 (0.49) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL15054936 | 0.83 | DGAT1 (0.69) | DGAT1KCNH2ADORA2A | |
| SCHEMBL15054895 | 0.83 | DGAT1 (0.69) | DGAT1KCNH2ADORA2A | |
| SCHEMBL15054893 | 0.83 | DGAT1 (0.69) | DGAT1KCNH2ADORA2A | |
| SCHEMBL14235869 | 0.83 | HRH3 (0.42) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL14235050 | 0.81 | USP30 (0.48) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL15610704 | 0.81 | USP30 (0.48) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL360587 | 0.80 | FFAR4 (0.57) | DGAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | DGAT1, DGAT2, SOAT1 | DGAT1 1/4885KCNH2 2689/4885ADORA2A 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.