Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.65 |
| ▸ | TCF4 | P15884 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.61 |
| ▸ | METAP2 | P50579 | 2/20 | 0.55 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CBFB | Q13951 | 1/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128245 | 0.84 | ALDH1A1 (0.60) | CYP11B1TCF4CTNNB1NPC1CBFB | |
| SCHEMBL12402878 | 0.83 | NPC1 (0.68) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14971558 | 0.81 | NPC1 (0.66) | NPC1KDM4EALDH1A1DGAT1 | |
| SCHEMBL484150 | 0.80 | NPC1 (0.67) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4184286 | 0.79 | CYP11B1 (0.67) | CYP11B1TCF4CTNNB1METAP2METAP1 | |
| SCHEMBL6259639 | 0.79 | SMN1; SMN2 (0.76) | CYP11B1TCF4CTNNB1NPC1NR4A2 | |
| SCHEMBL28477377 | 0.79 | CYP11B1 (0.70) | CYP11B1TCF4CTNNB1METAP2METAP1 | |
| SCHEMBL19175768 | 0.78 | DGAT1 (0.64) | CYP11B1TCF4CTNNB1DGAT1 | |
| SCHEMBL8741804 | 0.78 | KDM4E (0.69) | CYP11B1TCF4CTNNB1NPC1NR4A2 | |
| SCHEMBL1687838 | 0.78 | NPC1 (0.58) | CYP11B1NPC1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | DGAT1, DGAT2, SOAT1 | CYP11B1 463/4885TCF4 2508/4885CTNNB1 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.