Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TNKS | O95271 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019829 | 0.84 | LATS1 (0.36) | KDM4EMAPTGAAMAPK1CYP1A2 | |
| SCHEMBL6302291 | 0.83 | KDM4E (0.40) | KDM4EMAPTGAAMAPK1 | |
| SCHEMBL14143504 | 0.82 | MAPT (0.36) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL1959338 | 0.80 | AS3MT (0.40) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6099648 | 0.80 | ALDH1A1 (0.45) | MAPTGAAMEN1KMT2ATNKS | |
| SCHEMBL8309976 | 0.78 | POLB (0.41) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL3355418 | 0.75 | LATS1 (0.36) | KDM4EMAPTGAAMAPK1CYP1A2 | |
| SCHEMBL6106735 | 0.75 | KDM4E (0.43) | KDM4EMAPTMEN1KMT2ATNKS | |
| SCHEMBL7107891 | 0.68 | KDM4E (0.36) | KDM4EGAARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11326239 | 0.67 | KMT2A (0.53) | KDM4EMAPTMEN1KMT2ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161573-A1 | PROCESS FOR THE PREPARATION OF IMIQUIMOD AND INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2008-07-03 | — | — | US | disclosed |
| US-20080161573-A1 | PROCESS FOR THE PREPARATION OF IMIQUIMOD AND INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2008-07-03 | — | — | US | disclosed |
| US-7301027-B2 | Process for the preparation of Imiquimod and intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-27 | — | — | US | disclosed |
| US-7301027-B2 | Process for the preparation of Imiquimod and intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161573-A1 | PROCESS FOR THE PREPARATION OF IMIQUIMOD AND INTERMEDIATES THEREOF | MYD88, TLR7, MAVS | KDM4E 1004/4885MAPT 4284/4885GAA 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.