Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3896058 | 0.92 | F10 (0.57) | F10NPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL3909803 | 0.86 | F10 (0.52) | F10NPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL14132304 | 0.76 | F10 (1.00) | F10NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14132044 | 0.75 | F10 (0.93) | F10NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3905687 | 0.75 | F10 (0.84) | F10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5540645 | 0.73 | MAPK1 (0.58) | F10NPC1RAB9AALDH1A1F2 | |
| SCHEMBL5541960 | 0.73 | SMN1; SMN2 (0.61) | F10SMN1; SMN2PLGPROCLMNA | |
| SCHEMBL3897912 | 0.73 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2RECQLNFKB1 | |
| SCHEMBL14599607 | 0.72 | F10 (0.63) | F10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14132141 | 0.72 | F10 (0.90) | F10NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |