Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909803 | 0.89 | F10 (0.52) | RAB9ANPC1SMN1; SMN2RECQLNFKB1 | |
| SCHEMBL3897181 | 0.77 | F10 (0.60) | RAB9ANPC1SMN1; SMN2RECQLCASP3 | |
| SCHEMBL3902858 | 0.76 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2RECQLCASP3 | |
| SCHEMBL3900132 | 0.75 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2GAAGFER | |
| SCHEMBL3912302 | 0.75 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2RECQLGAA | |
| SCHEMBL5536198 | 0.74 | NAMPT (0.64) | RAB9ANPC1ALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL5540070 | 0.74 | NAMPT (0.73) | SMN1; SMN2ALDH1A1GAANAMPTLMNA | |
| SCHEMBL17780681 | 0.73 | EPHX2 (0.49) | RAB9ANPC1NFKB1GFERCYP1A2 | |
| SCHEMBL14132280 | 0.73 | F10 (0.62) | RAB9ANPC1SMN1; SMN2RECQLNFKB1 | |
| SCHEMBL5546309 | 0.73 | NAMPT (0.67) | RAB9ANPC1L3MBTL1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |