Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431910 | 0.83 | LTB4R2 (0.49) | LTB4R2SLC6A4SLC6A3CHEK1MEN1 | |
| SCHEMBL7605663 | 0.83 | ALDH1A1 (0.44) | LTB4R2SLC6A4SLC6A3AGTR1MEN1 | |
| Hydrochloric Acid SCHEMBL7605670 | 0.83 | LTB4R2 (0.57) | LTB4R2AGTR1 | |
| SCHEMBL8871967 | 0.82 | SLC6A3 (0.69) | LTB4R2SLC6A4SLC6A3AGTR1 | |
| SCHEMBL29466501 | 0.80 | SLC6A3 (0.67) | SLC6A4SLC6A3CHEK1MEN1KMT2A | |
| SCHEMBL3905291 | 0.80 | SLC6A3 (0.67) | SLC6A4SLC6A3CHEK1MEN1KMT2A | |
| SCHEMBL1515723 | 0.80 | BCAT2 (0.59) | LTB4R2SLC6A4SLC6A3CHEK1MEN1 | |
| SCHEMBL294730 | 0.79 | BCAT2 (0.63) | CHEK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30955031 | 0.79 | BCAT2 (0.57) | SLC6A4SLC6A3CHEK1MEN1KMT2A | |
| SCHEMBL31125227 | 0.79 | BCAT2 (0.63) | CHEK1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393958-B2 | Triamide-substituted heterobicyclic compounds | PFIZER, INC. (US) | 2008-07-01 | — | — | US | disclosed |