Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MTTP | P55157 | 6/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993519 | 1.00 | KDM4E (0.48) | KDM4EF10PRSS1ALDH1A1MTTP | |
| SCHEMBL14132458 | 0.77 | MTTP (0.68) | MTTP | |
| SCHEMBL1600315 | 0.77 | MTTP (0.70) | MTTP | |
| SCHEMBL14186885 | 0.77 | MTTP (0.70) | MTTP | |
| SCHEMBL5669917 | 0.74 | PLAU (0.53) | PLAU | |
| SCHEMBL5669922 | 0.74 | HDAC1 (0.49) | ALDH1A1NAAAPLAU | |
| SCHEMBL3265641 | 0.72 | MTTP (0.70) | MTTP | |
| SCHEMBL5669411 | 0.72 | TLR2 (0.39) | PRSS1NAAAPLAU | |
| SCHEMBL20777191 | 0.70 | F10 (0.64) | KDM4EF10PRSS1MTTPCTSL | |
| SCHEMBL20777192 | 0.70 | F10 (0.64) | KDM4EF10PRSS1MTTPCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716137-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080373-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |