Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.49 |
| ▸ | AHCY | P23526 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134547 | 0.88 | AHCY (0.53) | P2RY2AHCYADORA2AADORA2BP2RY1 | |
| SCHEMBL13396511 | 0.87 | AHCY (0.64) | P2RY2AHCYP2RX3P2RX2P2RY1 | |
| SCHEMBL16406702 | 0.78 | P2RX3 (0.71) | P2RY2P2RX3P2RX2P2RY1SRC | |
| SCHEMBL16406149 | 0.78 | P2RX3 (0.71) | P2RY2P2RX3P2RX2P2RY1SRC | |
| SCHEMBL16406148 | 0.78 | P2RX3 (0.71) | P2RY2P2RX3P2RX2P2RY1SRC | |
| SCHEMBL14134511 | 0.77 | ADORA2A (0.47) | P2RY2AHCYADORA2AADORA2BP2RX3 | |
| SCHEMBL18269535 | 0.77 | P2RX3 (0.73) | P2RY2P2RX3P2RX2P2RY1SRC | |
| SCHEMBL13396418 | 0.74 | AHCY (0.73) | P2RY2AHCYADORA2AADORA2BP2RY1 | |
| SCHEMBL3316378 | 0.74 | AHCY (0.73) | P2RY2AHCYADORA2AADORA2BP2RY1 | |
| SCHEMBL3316367 | 0.74 | AHCY (0.73) | P2RY2AHCYADORA2AADORA2BP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324179-B2 | Nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |