SCHEMBL1413445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1413800	0.85	CXCR3 (0.46)	POLBHTR6
	SCHEMBL4006649	0.84	HTR6 (0.39)	LMNAHTR6SMN1; SMN2
	SCHEMBL1413506	0.83	HTR6 (0.59)	ALDH1A1KMT2AMAPK1POLBRAB9A
	SCHEMBL1413299	0.83	HTR6 (0.50)	KMT2ALMNAHTR6MEN1SMN1; SMN2
	SCHEMBL1413744	0.81	NAMPT (0.44)	LMNAHTTSMN1; SMN2
	SCHEMBL1413368	0.81	MEN1 (0.51)	ALDH1A1KMT2ALMNAHTR6MEN1
	SCHEMBL4012523	0.81	CXCR4 (0.48)	ALDH1A1KMT2ALMNAHTR6MEN1
	SCHEMBL1413495	0.77	ALDH1A1 (0.54)	ALDH1A1KMT2AMAPK1GAALMNA
	SCHEMBL1413662	0.76	HTR6 (0.57)	ALDH1A1KMT2AMAPK1POLBRAB9A
	SCHEMBL1413659	0.76	HTR6 (0.57)	ALDH1A1KMT2AMAPK1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.