Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021800 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL18837401 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL20065598 | 0.75 | TDP1 (0.41) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL16615842 | 0.74 | — | — | |
| SCHEMBL18993580 | 0.73 | — | — | |
| SCHEMBL22528342 | 0.71 | TDP1 (0.43) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL17733564 | 0.71 | TDP1 (0.40) | TDP1 | |
| SCHEMBL13450488 | 0.71 | — | — | |
| SCHEMBL17993968 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL19661047 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012160447-A1 | 3, 5 -DIPHENYL- SUBSTITUTED PYRAZOLINES FOR THE TREATMENT OF CANCER, PROLIFERATIVE, INFLAMMATORY OR AUTOIMMUNE DISEASES | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2012-11-29 | — | — | WO | disclosed |