Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14162642 | 0.80 | TDP1 (0.38) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL14327254 | 0.78 | ALDH1A1 (0.35) | TDP1ALDH1A1TSHRTHPO | |
| SCHEMBL18576177 | 0.78 | TDP1 (0.38) | TDP1 | |
| SCHEMBL16615842 | 0.78 | — | — | |
| SCHEMBL13444874 | 0.76 | LDHA (0.35) | TDP1ALDH1A1TSHRFGFR4 | |
| SCHEMBL24849584 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14136251 | 0.75 | TDP1 (0.38) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL20099336 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL12687030 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHRTHPO | |
| SCHEMBL14435611 | 0.74 | ALDH1A1 (0.30) | TDP1ALOX15ALDH1A1TSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192859-B2 | Quinoline compounds as modulators of RAGE activity and uses thereof | UNIV NEW YORK (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
| US-20190194136-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | UNIV NEW YORK (US) | 2019-06-27 | — | — | US | disclosed |
| WO-2018069515-A1 | NOVEL ROUTE FOR THE SYNTHESIS OF STATISTICAL, ALIPHATIC-AROMATIC COPOLYAMIDES AND THE RESULTING STATISTICAL, ALIPHATIC-AROMATIC COPOLYAMIDES | UNIVERSITÉ DE BORDEAUX (FR) | 2018-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | TDP1 1375/4885LMNA 2341/4885ALOX15 1580/4885 |
| US-20190194136-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | AGER, HMGB1, GPR119 | TDP1 1686/4885LMNA 793/4885ALOX15 806/4885 |
| US-11192859-B2 | Quinoline compounds as modulators of RAGE activity and uses thereof | AGER, HMGB1, GPR119 | TDP1 1686/4885LMNA 793/4885ALOX15 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.