Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.66 |
| ▸ | PGR | P06401 | 9/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138795 | 0.92 | NR3C1 (0.69) | NR3C1PGRNR3C2AR | |
| SCHEMBL14138793 | 0.87 | NR3C1 (0.60) | NR3C1PGRNR3C2AR | |
| SCHEMBL14138956 | 0.84 | NR3C1 (0.58) | NR3C1PGRNR3C2AR | |
| SCHEMBL14139103 | 0.82 | PGR (0.58) | NR3C1PGRNR3C2AR | |
| SCHEMBL13759957 | 0.80 | PGR (0.54) | NR3C1PGRNR3C2AR | |
| SCHEMBL4176699 | 0.79 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL14139077 | 0.79 | NR3C1 (0.50) | NR3C1PGRNR3C2AR | |
| SCHEMBL14138797 | 0.78 | PGR (0.59) | NR3C1PGRNR3C2AR | |
| SCHEMBL14138790 | 0.78 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL14138787 | 0.77 | PGR (0.60) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1944290-A1 | NOVEL 1-2-DIHYDROQUINOLINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |