SCHEMBL14141908

SCHEMBL14141908

CC(C)(C)OC(=O)N1CC=C(c2cnc(COc3ccc(S(C)(=O)=O)cc3)cn2)CC1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14141809 0.88 GPR119 (0.54) GPR119
SCHEMBL1655856 0.88 GPR119 (0.71) GPR119
SCHEMBL1577600 0.88 GPR119 (0.71) GPR119
SCHEMBL14141775 0.83 GPR119 (0.50) GPR119
SCHEMBL1577606 0.82 GPR119 (0.72) GPR119
SCHEMBL1578063 0.81 GPR119 (0.64) GPR119
SCHEMBL14141844 0.80 GPR119 (0.51) GPR119
SCHEMBL1577601 0.79 GPR119 (0.62) GPR119
SCHEMBL1577836 0.79 GPR119 (0.62) GPR119
SCHEMBL1577837 0.79 GPR119 (0.62) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190192510-A1 GPR119 AGONIST NIPPON CHEMIPHAR CO., LTD. (JP) 2019-06-27 — — US disclosed
EP-2532656-A1 GPR119 AGONIST Nippon Chemiphar Co., Ltd. (JP) 2012-12-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190192510-A1 GPR119 AGONIST GPR119, GPR4, GPR27 GPR119 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback