Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | RAD51 | Q06609 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215221 | 0.85 | HIF1A (0.52) | ALDH1A1RAD51KDM4EHPGDGAA | |
| SCHEMBL4326394 | 0.77 | RORC (0.57) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL18031314 | 0.74 | MAP2K3 (0.54) | ALDH1A1RAD51KDM4EHPGDMEN1 | |
| SCHEMBL31612337 | 0.74 | RAD51 (0.72) | ALDH1A1RAD51KDM4EHPGDMAPT | |
| SCHEMBL21360469 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGAANPC1 | |
| SCHEMBL18033605 | 0.72 | RORC (0.53) | ALDH1A1RAD51KDM4EHPGDMEN1 | |
| SCHEMBL7038860 | 0.71 | RAD51 (0.49) | ALDH1A1RAD51KDM4EHPGDGAA | |
| SCHEMBL20674509 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDGAAL3MBTL1 | |
| SCHEMBL29390070 | 0.70 | RORC (0.59) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1429286 | 0.70 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085302-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |