SCHEMBL1414348

SCHEMBL1414348

CC(C)(C)OC(=O)C#CC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
CTSK P43235 4/20 0.33
USP2 O75604 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ELANE P08246 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2946741 0.89 DGAT1 (0.44) DGAT1CTSKALDH1A1TDP1CA1
SCHEMBL18186430 0.89 DGAT1 (0.34) DGAT1CTSK
SCHEMBL16445931 0.89 DGAT1 (0.34) DGAT1CTSK
SCHEMBL20657046 0.89 DGAT1 (0.34) DGAT1CTSK
SCHEMBL16885807 0.88 DGAT1 (0.37) DGAT1CTSKUSP2SMN1; SMN2TDP1
SCHEMBL3489322 0.86 DGAT1 (0.36) DGAT1CTSK
SCHEMBL19216979 0.86 DGAT1 (0.36) DGAT1CTSK
SCHEMBL1088416 0.86 CTSK (0.38) DGAT1CTSKELANE
SCHEMBL19912070 0.84 DGAT1 (0.34) DGAT1CTSK
SCHEMBL1088806 0.80 CTSK (0.35) DGAT1CTSKCA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-15 US claimed
CN-114149444-B Method for synthesizing 2,3,6,7-anthracene tetracarboxylic dianhydride 常州市阳光药业有限公司 2022-11-15 CN claimed
CN-114149444-A Synthesis method of 2,3,6, 7-anthracene tetracarboxylic dianhydride 常州市阳光药业有限公司 2022-03-08 CN claimed
EP-4240433-B1 MEDICAL SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITION ELKEM SILICONES SHANGHAI CO LTD (CN) 2025-12-24 EP disclosed
US-20250352692-A1 MEDICAL SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITION ELKEM SILICONES FRANCE SAS (FR) 2025-11-20 US disclosed
US-12453800-B2 Medical silicone pressure-sensitive adhesive composition ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2025-10-28 US disclosed
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-15 US disclosed
CN-119213094-A Medical silicone pressure sensitive adhesive composition 埃肯有机硅法国简易股份公司 2024-12-27 CN disclosed
US-12037459-B2 Additive organopolysiloxane composition, curable composition, and film DOW SILICONES CORPORATION 2024-07-16 US disclosed
CN-117820323-A Synthesis method of pyrazolone spiro-dihydropyrrole derivative 安徽工程大学 2024-04-05 CN disclosed
US-20240009343-A1 MEDICAL SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITION ELKEM SILICONES FRANCE SAS (FR) 2024-01-11 US disclosed
WO-2003045384-A1 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES WARNER-LAMBERT COMPANY LLC (US) 2003-06-05 WO disclosed
EP-1314426-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases WARNER-LAMBERT COMPANY (US) 2003-05-28 EP disclosed
EP-1045836-A1 PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2000-10-25 EP disclosed
WO-1999031066-A1 PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1999-06-24 WO disclosed
WO-1998046652-A1 SUBSTITUTED POLY(PHENYLENEVINYLENE)S AND POLY(NAPTHALENEVINYLENE)S CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-10-22 WO disclosed
US-5439516-A Consists of an electron donating color forming organic compound, a heat activator and a color developer; used as recording material NIPPON PAINT CO., LTD. (JP) 1995-08-08 US disclosed
US-5140013-A Shelf life; polymerization inhibition; nontoxic; side effects reduction UNIVERSITE LAVAL (CA) 1992-08-18 US disclosed
WO-1991008775-A2 MALEIC ANHYDRIDE DERIVATIVES USED AS CONJUGATION AGENTS OF ANTI-TUMOR AGENTS ON DESIRED CARRIERS UNIVERSITE LAVAL (CA) 1991-06-27 WO disclosed
US-4764368-A Acid-cleavable compound DANA-FARBER CANCER INSTITUTE, INC. (US) 1988-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives ERG28, CYP17A1, AR DGAT1 3597/4885CTSK 4303/4885USP2 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.