Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.47 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144315 | 0.76 | NR3C1 (0.52) | NR3C1PGR | |
| SCHEMBL14144339 | 0.75 | NR3C1 (0.43) | NR3C1PGR | |
| SCHEMBL4733247 | 0.69 | NR3C1 (0.70) | NR3C1PGR | |
| SCHEMBL10279853 | 0.69 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL10280471 | 0.68 | NR3C1 (0.59) | NR3C1PGR | |
| SCHEMBL25590940 | 0.68 | ESR1 (0.61) | — | |
| SCHEMBL14144032 | 0.65 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL837107 | 0.65 | NR3C1 (0.74) | NR3C1PGR | |
| SCHEMBL837072 | 0.65 | NR3C1 (0.74) | NR3C1PGR | |
| SCHEMBL13315372 | 0.65 | NR3C1 (0.46) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079073-A1 | INDAZOLYL SULPHONAMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-07-03 | — | — | WO | disclosed |