Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144304 | 0.79 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL14144337 | 0.78 | NR3C1 (0.61) | NR3C1PGRAR | |
| SCHEMBL14144150 | 0.77 | NR3C1 (0.49) | NR3C1PGRAR | |
| SCHEMBL14144305 | 0.75 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL4784361 | 0.75 | NR3C1 (0.54) | NR3C1PGRAR | |
| SCHEMBL4784359 | 0.75 | NR3C1 (0.54) | NR3C1PGRAR | |
| SCHEMBL4738144 | 0.75 | NR3C1 (0.74) | NR3C1PGR | |
| SCHEMBL10280277 | 0.73 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL25214054 | 0.72 | ESR1 (0.50) | PKMESR1ESR2 | |
| SCHEMBL25266996 | 0.72 | ESR1 (0.50) | PKMESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079073-A1 | INDAZOLYL SULPHONAMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-07-03 | — | — | WO | disclosed |