Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693346 | 0.85 | FAAH (0.56) | NR1H4PPARGPPARAFAAHMMP2 | |
| SCHEMBL4688189 | 0.75 | NR1H4 (0.61) | NR1H4PPARGPPARAMAPTCHRNB2 | |
| SCHEMBL14144717 | 0.75 | NR1H4 (0.61) | NR1H4PPARGPPARAFAAHMAPT | |
| SCHEMBL5025661 | 0.73 | FAAH (0.55) | FAAHMMP2MMP13MMP14MAPT | |
| SCHEMBL4692597 | 0.71 | FAAH (0.57) | PPARGPPARAFAAHMAPTCYP2C9 | |
| SCHEMBL4689835 | 0.71 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL4693449 | 0.69 | FAAH (0.59) | FAAHMMP2MMP13MMP14 | |
| SCHEMBL4692571 | 0.69 | PPARG (0.57) | PPARGPPARAFAAHMAPTCYP2C9 | |
| SCHEMBL4688177 | 0.69 | PPARG (0.56) | PPARGPPARAFAAHMAPTCYP2C9 | |
| SCHEMBL15378572 | 0.68 | FAAH (0.58) | FAAHMMP2MMP13MMP14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | disclosed |