Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295193 | 0.82 | KCNH3 (0.54) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL2064760 | 0.80 | MAPT (0.57) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL11015521 | 0.79 | MAPT (0.44) | ALDH1A1GAAMAPTPOLBKCNH3 | |
| SCHEMBL1533580 | 0.78 | KCNH3 (0.57) | ALDH1A1MAPTKCNH3 | |
| Hydrochloric Acid SCHEMBL5967153 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL186867 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL9581125 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL23961126 | 0.75 | KCNH3 (0.66) | ALDH1A1MAPTKCNH3 | |
| SCHEMBL9412164 | 0.75 | IDO1 (0.47) | MAOAMAOBALDH1A1GAAMEN1 | |
| SCHEMBL6583061 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209397143-U | A kind of 4- fluoroaniline production with a variety of safeguard structures applies kettle with Methanol Recovery | 江苏健谷化工有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-109293474-A | A kind of 4- fluoroaniline production with a variety of safeguard structures applies kettle with Methanol Recovery | 江苏健谷化工有限公司 | 2019-02-01 | — | — | CN | disclosed |
| EP-1506962-B1 | Nitrogen-containing aromatic heterocycles | EISAI R&D MAN CO LTD (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1415987-B1 | NITROGENOUS AROMATIC RING COMPOUNDS AS ANTI CANCER AGENTS | EISAI R&D MAN CO LTD (JP) | 2007-02-28 | — | — | EP | disclosed |