Sugi Predict

Sugi Predict / Compounds / SCHEMBL186867

SCHEMBL186867

SCHEMBL186867

O=C(O)CNc1ccc(F)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.47
▸ GAA P10253 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ GRK2 P25098 2/20 0.45
▸ CA12 O43570 1/20 0.45
▸ CA1 P00915 1/20 0.45
▸ CA2 P00918 1/20 0.45
▸ CA7 P43166 1/20 0.45
▸ MITF O75030 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ P4HTM Q9NXG6 1/20 0.44
▸ ACHE P22303 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ TGM2 P21980 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5967153 1.00 ALDH1A1 (0.47) ALDH1A1GAANPC1RAB9AGRK2
SCHEMBL6583061 0.98 ALDH1A1 (0.45) ALDH1A1GAANPC1RAB9AGRK2
SCHEMBL28847224 0.98 ALDH1A1 (0.45) ALDH1A1GAANPC1RAB9AGRK2
SCHEMBL5692310 0.89 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ACA12CA1
Hydrochloric Acid SCHEMBL5839050 0.83 ALDH1A1 (0.53) ALDH1A1GAAGRK2CA12CA1
2-Ethoxyethanol SCHEMBL27751702 0.81 KCNH3 (0.45) ALDH1A1GAARAB9AMEN1KMT2A
SCHEMBL8361563 0.81 ALDH1A1 (0.46) ALDH1A1GAANPC1RAB9AGRK2
SCHEMBL5518500 0.81 ALDH1A1 (0.55) ALDH1A1GAAGRK2CA12CA1
SCHEMBL2703268 0.81 POLB (0.61) ALDH1A1GAANPC1RAB9AMEN1
SCHEMBL12419484 0.81 GAA (0.48) ALDH1A1GAAGRK2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 — — US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 — — US claimed
CN-113480485-B 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2023-04-07 — — CN claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 — — US claimed
US-20210032304-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2021-02-04 — — US claimed
EP-3752174-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF University of Florida Research Foundation, Incorporated (US) 2020-12-23 — — EP claimed
CN-111936157-A Fibroblast growth factor analogs and uses thereof 佛罗里达大学研究基金会 2020-11-13 — — CN claimed
CN-111285776-A Green synthesis method of visible light catalytic 1, 2-diamine compound 杭州师范大学 2020-06-16 — — CN claimed
WO-2019160910-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2019-08-22 — — WO claimed
US-20050042726-A1 Metabolic engineering of viomycin biosynthesis WISCONSIN ALUMNI RESEARCH FOUNDATION 2005-02-24 — — US claimed
EP-1260511-B1 Process for the preparation of 5-chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)indole and method of manufacturing sertindole LUNDBECK & CO AS H (DK) 2004-12-29 — — EP claimed
US-20040186146-A1 Amide of r-2-(aminoaryl)-propionic acid for use in theprevention of leucocyte activation DOMPÉ FARMACEUTICI S.P.A. (IT) 2004-09-23 — — US claimed
CN-1506350-A Process for producing N-(4-fluobenzene radical)-N-(2-hydroxy-4-chlorobenzene group) glycocoll H.¡�±������޹�˾ 2004-06-23 — — CN claimed
EP-0983264-B1 METHOD OF MANUFACTURING SERTINDOLE LUNDBECK & CO AS H (DK) 2004-02-04 — — EP claimed
EP-1260511-A1 Process for the preparation of 5-chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)indole and method of manufacturing sertindole H. Lundbeck A/S (DK) 2002-11-27 — — EP claimed
US-6335463-B1 Method of manufacturing sertindole H. LUNDBECK A/S (DK) 2002-01-01 — — US claimed
CN-1261363-A Process for the manufacture of sertindole LUNDBECK & CO AS H (DK) 2000-07-26 — — CN claimed
EP-0983264-A1 METHOD OF MANUFACTURING SERTINDOLE H. LUNDBECK A/S (DK) 2000-03-08 — — EP claimed
WO-1998051685-A1 METHOD OF MANUFACTURING SERTINDOLE H. LUNDBECK A/S (DK) 1998-11-19 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM ALDH1A1 4622/4885GAA 2546/4885NPC1 4677/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC ALDH1A1 981/4885GAA 1001/4885NPC1 2013/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM ALDH1A1 4622/4885GAA 2546/4885NPC1 4677/4885
US-20040186146-A1 Amide of r-2-(aminoaryl)-propionic acid for use in theprevention of leucocyte activation MMP8, CXCL8, HCAR2 ALDH1A1 391/4885GAA 3800/4885NPC1 1234/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT ALDH1A1 789/4885GAA 1925/4885NPC1 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.