SCHEMBL14145779

SCHEMBL14145779

Cc1ccc(S(=O)(=O)N(C2C=CCCC2)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
MAPT P10636 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
CNR1 P21554 3/20 0.40
CNR2 P34972 3/20 0.40
ALDH1A1 P00352 2/20 0.39
ACHE P22303 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
C5AR1 P21730 1/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
AGER Q15109 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
TAS2R14 Q9NYV8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13922031 0.77 CNR1 (0.39) HTR2AHTR2CMAPTMCOLN3CNR1
SCHEMBL12269802 0.74 ALDH1A1 (0.58) HTR2AHTR2CMCOLN3ALDH1A1ACHE
SCHEMBL14062319 0.74 ACHE (0.49) HTR2AHTR2CMAPTMCOLN3CNR1
SCHEMBL28096920 0.73 ALDH1A1 (0.41) MAPTMCOLN3ALDH1A1ACHECYP3A4
SCHEMBL4385251 0.70 ALDH1A1 (0.56) MAPTALDH1A1CYP3A4TSHRHTT
SCHEMBL22761738 0.69
SCHEMBL28010137 0.68 ALDH1A1 (0.43) HTR2AHTR2CMAPTMCOLN3CNR1
SCHEMBL8551770 0.68 CYP2D6 (0.40) MAPTALDH1A1ACHECYP3A4TSHR
SCHEMBL11116465 0.67 CNR1 (0.50) HTR2AHTR2CMAPTMCOLN3CNR1
SCHEMBL9460275 0.66 CNR1 (0.38) HTR2ACNR1CNR2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012160112-A1 NOVEL IODINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF AS AMINATION AGENTS FUNDACIÓ PRIVADA INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) 2012-11-29 WO disclosed