SCHEMBL1414580

SCHEMBL1414580

CC=CC=CC(=O)OC(CC)[Si](OC)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230355 1.00 ALDH1A1 (0.31) ALDH1A1LMNAMAPK1HTT
SCHEMBL758924 0.88
SCHEMBL2672112 0.88
SCHEMBL4312008 0.86 HCAR2 (0.36)
SCHEMBL9575669 0.86 HCAR2 (0.36)
SCHEMBL4312022 0.86 HCAR2 (0.36)
SCHEMBL14993404 0.86 LMNA (0.30) LMNAMAPK1HTT
SCHEMBL7096197 0.81 HCAR2 (0.46) ALDH1A1
SCHEMBL7096200 0.81 HCAR2 (0.46) ALDH1A1
SCHEMBL23149457 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294101-B1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORP (US) 2018-10-17 EP disclosed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
EP-2521752-B1 ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP DOW CORNING (US) 2017-10-25 EP disclosed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
US-9493615-B2 Organopolysiloxanes containing an unsaturated group DOW CORNING CORPORATION (US) 2016-11-15 US disclosed
EP-2788436-B1 TREATMENT OF FILLER WITH SILANE DOW CORNING (US) 2016-10-12 EP disclosed
US-9080057-B2 Treatment of filler with silane DOW CORNING CORPORATION (US) 2015-07-14 US disclosed
US-20140350152-A1 Treatment Of Filler With Silane DOW SILICONES CORPORATION 2014-11-27 US disclosed
US-8476375-B2 Polymers modified by silanes DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
WO-2013083748-A1 TREATMENT OF FILLER WITH SILANE DOW CORNING CORPORATION (US) 2013-06-13 WO disclosed
WO-2013083746-A1 TREATMENT OF FILLER WITH SILANE DOW CORNING CORPORATION (US) 2013-06-13 WO disclosed
WO-2013081820-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW CORNING CORPORATION (US) 2013-06-06 WO disclosed
EP-2521752-A1 ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP Dow Corning Corporation (US) 2012-11-14 EP disclosed
US-20120283362-A1 ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP DOW SILICONES CORPORATION 2012-11-08 US disclosed
US-20110178198-A1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORPORATION 2011-07-21 US disclosed
WO-2011083044-A1 ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP DOW CORNING CORPORATION (US) 2011-07-14 WO disclosed
EP-2294101-A1 POLYMERS MODIFIED BY SILANES Dow Corning Corporation (US) 2011-03-16 EP disclosed
WO-2010000479-A1 POLYMERS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-01-07 WO disclosed