Isophthalic Acid

Isophthalic Acid

SCHEMBL1414739

C1CCCCC1.O=C(O)c1ccc(C(=O)O)c2c1CC2.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
KMO O15229 2/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA6 P23280 1/20 0.47
CA9 Q16790 1/20 0.47
HPGD P15428 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP2C9 P11712 3/20 0.45
CYP2D6 P10635 2/20 0.45
CYP1A2 P05177 2/20 0.45
HIF1A Q16665 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
MRGPRX4 Q96LA9 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL381836 0.96 KDM4E (0.52) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL1537969 0.95 KMO (0.47) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL381642 0.93 KDM4E (0.49) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL2468458 0.93 RXRA (0.50) KDM4EKMOCA12CA1CA2
Benzoic Acid SCHEMBL8735129 0.84 TSHR (0.61) KDM4EKMOCA12CA1CA2
Cyclohexane SCHEMBL483378 0.84 CYP1A2 (0.57) KDM4ECA12CA1CA2CA6
Isophthalic Acid SCHEMBL259039 0.82 KMO (0.60) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL6857089 0.82 KMO (0.60) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL27962393 0.82 KMO (0.60) KDM4EKMOCA12CA1CA2
Isophthalic Acid SCHEMBL247733 0.81 KDM4E (0.49) KDM4EKMOCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558807-B1 DRYER FABRIC WITH AIR CHANNELS ON THE BACKSIDE ALBANY INT CORP (US) 2008-12-31 EP claimed
US-8030382-B2 Polylactic acid composition TEIJIN LIMITED (JP) 2011-10-04 US disclosed
US-20110092622-A1 NON-HALOGEN FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-04-21 US disclosed
EP-2295501-A1 NON-HALOGEN FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION Adeka Corporation (JP) 2011-03-16 EP disclosed
WO-1995027818-A1 MONOFILAMENTS FROM POLYMER BLENDS AND FABRICS THEREOF SHAKESPEARE COMPANY (US) 1995-10-19 WO disclosed