Isophthalic Acid

Isophthalic Acid

SCHEMBL381836

O=C(O)c1ccc(C(=O)O)c2c1CC2.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA6 P23280 1/20 0.50
CA9 Q16790 1/20 0.50
CYP1A2 P05177 3/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP2C9 P11712 2/20 0.47
KMO O15229 2/20 0.47
PTPN1 P18031 1/20 0.46
UNG P13051 1/20 0.46
ALDH1A1 P00352 2/20 0.44
DAO P14920 1/20 0.44
TSHR P16473 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL1414739 0.96 KDM4E (0.49) KDM4ECA12CA1CA2CA6
Isophthalic Acid SCHEMBL381642 0.92 KDM4E (0.49) KDM4ECA12CA1CA2CA6
Isophthalic Acid SCHEMBL2468458 0.92 RXRA (0.50) KDM4ECA12CA1CA2CA6
Isophthalic Acid SCHEMBL1537969 0.91 KMO (0.47) KDM4ECA12CA1CA2CA6
Benzoic Acid SCHEMBL8735129 0.88 TSHR (0.61) KDM4ECA12CA1CA2CA6
Terephthalic Acid SCHEMBL7603708 0.83 TSHR (0.57) KDM4ECA12CA1CA2CA6
SCHEMBL29769278 0.82 CYP1A2 (0.63) KDM4ECA12CA1CA2CA6
SCHEMBL21688 0.82 CYP1A2 (0.63) KDM4ECA12CA1CA2CA6
SCHEMBL8636470 0.82 KDM4E (0.50) KDM4ECYP1A2HPGDHSD17B10PTPN1
Sebacic Acid SCHEMBL11230503 0.81 HDAC3 (0.45) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102918185-B Surface treatment bath, the method using described surface treatment bath production surface-treated steel plate and the surface-treated steel plate utilizing described production method to be formed TOYO SEIKAN CO.,LTD. (JP) 2015-12-09 CN disclosed
US-20120028047-A1 Fiber reinforced resin composition, molding material, and method for producing fiber reinforced resin composition TORAY INDUSTRIES, INC. (JP) 2012-02-02 US disclosed
EP-2410021-A1 FIBER REINFORCED RESIN COMPOSITION, MOLDING MATERIAL, AND METHOD FOR PRODUCING FIBER REINFORCED RESIN COMPOSITION Toray Industries, Inc. (JP) 2012-01-25 EP disclosed
US-20110269907-A1 RESIN COMPOSITION AND MOLDED ARTICLE MADE THEREOF TORAY INDUSTRIES, INC. (JP) 2011-11-03 US disclosed
EP-2380883-A1 CYCLIC CARBODIIMIDE COMPOUNDS Teijin Limited (JP) 2011-10-26 EP disclosed
US-20110251384-A1 CYCLIC CARBODIIMIDE COMPOUNDS TEIJIN LIMITED (JP) 2011-10-13 US disclosed
EP-2374833-A1 METHOD FOR USING CYCLIC CARBODIMIDE Teijin Limited (JP) 2011-10-12 EP disclosed
US-20110237755-A1 METHOD OF USING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2011-09-29 US disclosed
US-7999021-B2 Resin composition and molded article made thereof TORAY INDUSTRIES, INC. (JP) 2011-08-16 US disclosed
US-7960464-B2 Thermoplastic resin composition and molded article TORAY INDUSTRIES, INC. (JP) 2011-06-14 US disclosed
EP-0492582-A2 Copolyesters having an improved combination of properties ISTITUTO GUIDO DONEGANI S.p.A. (IT) 1992-07-01 EP disclosed
US-4999229-A Ethylene-vinyl alcohol copolymer and blend with polyamide, polyolefin, polyester or polycarbonate KURARAY CO., LTD. (JP) 1991-03-12 US disclosed
US-4966830-A Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-10-30 US disclosed
EP-0300410-A2 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1989-01-25 EP disclosed
US-4296218-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1981-10-20 US disclosed
US-4251649-A COMPRISING A LOW MOLECULAR WEIGHT MODIFIER POLYESTER AND A POLYFUNCTIONAL HYDROXY OR AMINE TEIJIN LIMITED (JP) 1981-02-17 US disclosed
US-4220563-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1980-09-02 US disclosed
US-4137221-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1979-01-30 US disclosed
US-4134884-A Curable resinous composition comprising unsaturated alkyd and unsaturated cycloacetal SHOWA HIGHPOLYMER CO., LTD. (JP) 1979-01-16 US disclosed
US-4038257-A HIGH STRENGTH, CORROSION RESISTANCE TOYO BOSEKI KABUSHIKI KAISHA (JA) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251384-A1 CYCLIC CARBODIIMIDE COMPOUNDS APEX1, LIG4, EPB41 KDM4E 64/4885CA12 3252/4885CA1 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.