Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.59 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19389647 | 1.00 | ALDH1A1 (0.59) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL3563509 | 0.95 | ALDH1A1 (0.65) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL21156471 | 0.88 | ALDH1A1 (0.55) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL15952644 | 0.88 | ALDH1A1 (0.63) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL15952047 | 0.87 | ALDH1A1 (0.57) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL16360861 | 0.86 | FDPS (0.71) | ALDH1A1FDPSMAPTHPGDCYP1A2 | |
| SCHEMBL31268362 | 0.86 | FDPS (0.71) | ALDH1A1FDPSMAPTHPGDCYP1A2 | |
| SCHEMBL30802598 | 0.86 | FDPS (0.71) | ALDH1A1FDPSMAPTHPGDCYP1A2 | |
| SCHEMBL27262670 | 0.85 | ALDH1A1 (0.51) | ALDH1A1AOX1FDPSMAPTHPGD | |
| SCHEMBL1515911 | 0.83 | ALDH1A1 (0.69) | ALDH1A1AOX1FDPSMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080015-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. (US) | 2008-07-03 | — | — | WO | disclosed |