Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19541101 | 0.85 | DPP7 (0.40) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL23897737 | 0.85 | DPP7 (0.40) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL607463 | 0.83 | DPP7 (0.44) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL18866881 | 0.83 | DPP7 (0.44) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL3169670 | 0.83 | DPP7 (0.44) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL5872015 | 0.82 | DPP7 (0.41) | DPP7OTCDDAH1GNAI3GNAO1 | |
| L-Citrulline SCHEMBL15909604 | 0.82 | OTC (0.59) | OTCDDAH1ARG1ALOX15BLM | |
| L-Citrulline SCHEMBL215403 | 0.82 | OTC (0.59) | OTCDDAH1ARG1ALOX15BLM | |
| L-Citrulline SCHEMBL15909605 | 0.82 | OTC (0.59) | OTCDDAH1ARG1ALOX15BLM | |
| L-Citrulline SCHEMBL22426116 | 0.82 | OTC (0.59) | OTCDDAH1ARG1ALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323656-B2 | Antigen determinant of rheumatoid arthritis-specific autoantibody and use thereof | XU YIJUN (CA) | 2012-12-04 | — | — | US | disclosed |