Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 7/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148738 | 0.80 | EGFR (0.69) | EGFR | |
| SCHEMBL14148802 | 0.79 | TTR (0.46) | EGFRBACE1 | |
| SCHEMBL17356365 | 0.75 | EGFR (0.38) | EGFR | |
| SCHEMBL14148735 | 0.75 | EGFR (0.43) | EGFR | |
| SCHEMBL8125136 | 0.73 | EGFR (0.50) | EGFRMCHR1 | |
| SCHEMBL8125134 | 0.73 | EGFR (0.50) | EGFRMCHR1 | |
| SCHEMBL4731185 | 0.72 | EGFR (0.45) | EGFR | |
| SCHEMBL14148803 | 0.72 | EGFR (0.40) | EGFR | |
| SCHEMBL6171017 | 0.70 | ALDH1A1 (0.47) | APP | |
| SCHEMBL6171023 | 0.70 | ALDH1A1 (0.47) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053479-A9 | SELF-IMMOLATIVE POLYMERS | UNIV RAMOT (IL) | 2008-07-17 | — | — | WO | disclosed |