Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148803 | 0.82 | EGFR (0.40) | EGFRALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL14148738 | 0.81 | EGFR (0.69) | EGFRALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL17356365 | 0.79 | EGFR (0.38) | EGFRALDH1A1KDM4EGAAMAPT | |
| SCHEMBL28010950 | 0.75 | PAM (0.58) | PAMPDE5AALDH1A1ALOX15CYP2D6 | |
| SCHEMBL14148734 | 0.72 | IAPP (0.48) | EGFR | |
| SCHEMBL14148802 | 0.71 | TTR (0.46) | EGFRCA12CA1CA2CA7 | |
| SCHEMBL23540351 | 0.70 | PAM (0.43) | PAMPDE5AALDH1A1ALOX15CYP2D6 | |
| SCHEMBL14148735 | 0.70 | EGFR (0.43) | EGFRALDH1A1ALOX15KDM4EGAA | |
| SCHEMBL18556990 | 0.68 | EGFR (0.31) | EGFR | |
| SCHEMBL19419446 | 0.67 | ALDH1A1 (0.75) | ALDH1A1CDC25BCASP6RCE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053479-A9 | SELF-IMMOLATIVE POLYMERS | UNIV RAMOT (IL) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008053479-A1 | SELF-IMMOLATIVE POLYMERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-05-08 | — | — | WO | disclosed |