SCHEMBL141491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL141492	1.00	KDM4E (0.48)	KDM4EKMT2AGAAALDH1A1HPGD
	SCHEMBL141941	0.83	PDE4B (0.45)	KDM4EALDH1A1SMN1; SMN2LMNAPDE4B
	SCHEMBL29440158	0.83	PDE4B (0.45)	KDM4EALDH1A1SMN1; SMN2LMNAPDE4B
	SCHEMBL142116	0.82	KDM4E (0.59)	KDM4EKMT2AGAAALDH1A1HPGD
	SCHEMBL112198	0.82	KDM4E (0.50)	KDM4EKMT2AGAAALDH1A1HPGD
	SCHEMBL7353686	0.78	PDE4B (0.61)	KDM4EKMT2AGAAALDH1A1HPGD
	SCHEMBL7353680	0.78	PDE4B (0.61)	KDM4EKMT2AGAAALDH1A1HPGD
	SCHEMBL17936307	0.77	MAPT (0.42)	KDM4EKMT2AALDH1A1HPGDSMN1; SMN2
	SCHEMBL145748	0.76	KCNA3 (0.42)	KDM4EKMT2AALDH1A1HPGDMAPK1
	SCHEMBL145747	0.76	KCNA3 (0.42)	KDM4EKMT2AALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.