SCHEMBL142116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17124825	0.88	KDM4E (0.53)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL7353686	0.83	PDE4B (0.61)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL7353680	0.83	PDE4B (0.61)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL141492	0.82	KDM4E (0.48)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL141491	0.82	KDM4E (0.48)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL25185073	0.81	KDM4E (0.52)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL30383432	0.81	KDM4E (0.52)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL8072698	0.79	HDAC1 (0.67)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL8072695	0.79	HDAC1 (0.67)	KDM4EALDH1A1HSD17B10HPGDMAPK1
	SCHEMBL1569059	0.78	THRB (0.61)	KDM4EALDH1A1MAPK1ALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.