SCHEMBL1415239

SCHEMBL1415239

CCCCC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 10/20 0.39
TLR7 Q9NYK1 5/20 0.39
KCNH2 Q12809 9/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380417 0.93 SPHK1 (0.38) TLR8TLR7KCNH2
SCHEMBL8027997 0.89 KCNH2 (0.35) TLR8TLR7KCNH2
SCHEMBL8201839 0.81 LMNA (0.31)
SCHEMBL8377084 0.80 TLR8 (0.38) TLR8TLR7KCNH2
SCHEMBL3809510 0.80 TLR8 (0.37) TLR8TLR7KCNH2
SCHEMBL27642131 0.79 TSHR (0.35) TLR8TLR7KCNH2
SCHEMBL2784655 0.77 SLC29A1 (0.45) TLR8TLR7
SCHEMBL6700072 0.77 HTR7 (0.33)
Methoxymethane SCHEMBL27642128 0.76 NPC1 (0.31)
SCHEMBL11368962 0.76 TLR8 (0.38) TLR8TLR7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520182-B1 Condensates of sulphonated phenols, urea, other organic nitrogen containing bases and formaldehyde and their use as tanning agent or as spray composition for redispersable polymer powders BASF AG (DE) 1996-03-20 EP claimed
US-8372161-B2 Method for the reactive coloring of leather BASF SE (DE) 2013-02-12 US disclosed
EP-1682717-B1 METHOD FOR THE REACTIVE COLOURING OF LEATHER, DYESTUFFS AND THEIR USE BASF SE (DE) 2011-03-16 EP disclosed
US-20070033746-A1 Method for the reactive coloring of leather BASF AKTIENGESSELLSCHAFT (DE) 2007-02-15 US disclosed
EP-1682717-A1 METHOD FOR THE REACTIVE COLOURING OF LEATHER BASF Aktiengesellschaft (DE) 2006-07-26 EP disclosed
WO-2005040490-A1 METHOD FOR THE REACTIVE COLOURING OF LEATHER BASF AKTIENGESELLSCHAFT (DE) 2005-05-06 WO disclosed
US-6048610-A MALEIC ANHYDRIDE FUNCTIONALIZED CHLORINATED POLYOLEFIN, A MALEIC ANHYDRIDE FUNCTIONALIZED BLOCK POLYSTYRENE COPOLYMER, AND A CROSSLINKING AGENT. INTERTAPE POLYMER GROUP, INC. (US) 2000-04-11 US disclosed
EP-0520182-A1 Condensates of sulphonated phenols, urea, other organic nitrogen containing bases and formaldehyde and their use as tanning agent or as spray composition for redispersable polymer powders BASF Aktiengesellschaft (DE) 1992-12-30 EP disclosed
US-4855427-A Epoxy resins obtained from reaction of epoxyalkyl halides and aromatic hydroxyl-containing melamines BASF AKTIENGESELLSCHAFT (DE) 1989-08-08 US disclosed
US-4199646-A Heat-activatable, pressure-sensitive adhesive tape or sheet NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1980-04-22 US disclosed