SCHEMBL8201839

SCHEMBL8201839

CCC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HTR7 P34969 4/20 0.31
ADRA1D P25100 2/20 0.31
ADRA1A P35348 2/20 0.31
ADRA1B P35368 2/20 0.31
HTR2C P28335 1/20 0.31
HTR6 P50406 1/20 0.31
HRH4 Q9H3N8 1/20 0.30
TPH1 P17752 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6700072 0.96 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BHTR2C
Methoxymethane SCHEMBL27642128 0.94 NPC1 (0.31) HTR7ADRA1DADRA1AADRA1B
SCHEMBL27642131 0.85 TSHR (0.35) LMNAHTR7ADRA1DADRA1AADRA1B
SCHEMBL3295987 0.84 KMT2A (0.39) LMNA
SCHEMBL8027997 0.84 KCNH2 (0.35) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL5875882 0.82 ALDH1A1 (0.31)
SCHEMBL1415239 0.81 TLR8 (0.39)
SCHEMBL5284918 0.81 CYP1A2 (0.30)
SCHEMBL8380417 0.78 SPHK1 (0.38) LMNA
SCHEMBL10059800 0.77 L3MBTL1 (0.47) HTR7ADRA1DADRA1AADRA1BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066307-A Polyhydroxyalkyl melamine and amino resin AMERICAN CYANAMID COMPANY (US) 1991-11-19 US claimed
EP-0106049-B1 HYDROXYALKYLMELAMINE MODIFIED MELAMINE-FORMALDEHYDE RESINS AND THEIR USE IN HEAT AND PRESSURE CONSOLIDATED LAMINATES FORMICA CORPORATION (US) 1986-10-29 EP claimed
EP-0106049-A1 Hydroxyalkylmelamine modified melamine-formaldehyde resins and their use in heat and pressure consolidated laminates FORMICA CORPORATION (US) 1984-04-25 EP claimed
US-4424261-A IMPREGNATED CELLULOSIC PAPER AMERICAN CYANAMID COMPANY (US) 1984-01-03 US claimed
US-4414174-A POLYURETHANES WITH SOME SHORT CHAIN DIOLS REPLACED WITH HYDROXYALKYLMELAMINE AMERICAN CYANAMID COMPANY (US) 1983-11-08 US claimed
CN-100586976-C Melamine and guanamine based crosslinking compositions CYTEC TECH CORP 2010-02-03 CN disclosed
CN-1780866-A Melamine and guanamine based crosslinking compositions CYTEC TECH CORP (US) 2006-05-31 CN disclosed
US-6048610-A MALEIC ANHYDRIDE FUNCTIONALIZED CHLORINATED POLYOLEFIN, A MALEIC ANHYDRIDE FUNCTIONALIZED BLOCK POLYSTYRENE COPOLYMER, AND A CROSSLINKING AGENT. INTERTAPE POLYMER GROUP, INC. (US) 2000-04-11 US disclosed
EP-0496081-B1 Rigid polyurethane and polyisocyanurate foams CYTEC TECH CORP (US) 1997-04-16 EP disclosed
EP-0601402-B1 Process for producing impregnated paper for superficial coating BASF AG (DE) 1996-08-14 EP disclosed
EP-0601402-A1 Process for producing impregnated paper for superficial coating BASF Aktiengesellschaft (DE) 1994-06-15 EP disclosed
EP-0496081-A2 Rigid polyurethane and polyisocyanurate foams CYTEC TECHNOLOGY CORP. (US) 1992-07-29 EP disclosed
EP-0193092-A2 Strong and elastic polyurethane polyurea polycrylates and electron beam-cured coatings containing the same DeSOTO, INC. (US) 1986-09-03 EP disclosed
US-4591613-A AMINO RESINS AMERICAN CYANAMID COMPANY (US) 1986-05-27 US disclosed
US-4581407-A Strong and elastic polyurethane polyurea polycrylates and electron beam-cured coatings containing the same DESOTO, INC. (US) 1986-04-08 US disclosed
US-4499125-A Continuously produced melt reacted melamine-formaldehyde resins FORMICA CORPORATION (US) 1985-02-12 US disclosed
EP-0118674-A2 Method for continuously producing melt-reacted melamine-formaldehyde resins FORMICA CORPORATION (US) 1984-09-19 EP disclosed
US-4458062-A Continuously produced melt reacted melamine-formaldehyde resins AMERICAN CYANAMID COMPANY (US) 1984-07-03 US disclosed
US-4414174-A POLYURETHANES WITH SOME SHORT CHAIN DIOLS REPLACED WITH HYDROXYALKYLMELAMINE AMERICAN CYANAMID COMPANY (US) 1983-11-08 US disclosed
US-4199646-A Heat-activatable, pressure-sensitive adhesive tape or sheet NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1980-04-22 US disclosed