Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 4/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145936 | 0.85 | RECQL (0.60) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL25376970 | 0.83 | RECQL (0.58) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL10486766 | 0.83 | RECQL (0.54) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL10486765 | 0.83 | RECQL (0.62) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL146481 | 0.82 | TP53 (0.51) | MAPTALDH1A1TP53AKR1C4AKR1C3 | |
| SCHEMBL7931237 | 0.77 | CES2 (0.56) | RECQLRORBCES2CES1MAPT | |
| SCHEMBL50416 | 0.76 | CES2 (0.71) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL29399311 | 0.76 | CES2 (0.71) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL11842389 | 0.75 | RECQL (0.77) | RECQLRORBGABRPGABRDGABRA1 | |
| SCHEMBL145258 | 0.75 | RECQL (0.70) | RECQLRORBGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613819-B2 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2020-11-25 | — | — | EP | claimed |
| EP-2613819-B1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2018-01-10 | — | — | EP | claimed |
| US-8541498-B2 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD. (GB) | 2013-09-24 | — | — | US | claimed |
| EP-2613819-A1 | Lubricious coatings for medical devices | Biointeractions Ltd. (GB) | 2013-07-17 | — | — | EP | claimed |
| WO-2012032283-A1 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD (GB) | 2012-03-15 | — | — | WO | claimed |
| US-20120059111-A1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD. (GB) | 2012-03-08 | — | — | US | claimed |
| EP-2613819-B2 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2020-11-25 | — | — | EP | disclosed |
| EP-2613819-B1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2018-01-10 | — | — | EP | disclosed |
| US-8541498-B2 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD. (GB) | 2013-09-24 | — | — | US | disclosed |
| EP-2613819-A1 | Lubricious coatings for medical devices | Biointeractions Ltd. (GB) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032283-A1 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD (GB) | 2012-03-15 | — | — | WO | disclosed |
| US-20120059111-A1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD. (GB) | 2012-03-08 | — | — | US | disclosed |