SCHEMBL145258

SCHEMBL145258

O=C(c1cc(Cl)ccc1O)c1ccccc1Cl

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.70
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
GABRP O00591 1/20 0.55
GABRD O14764 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRB1 P18505 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55
GABRA5 P31644 1/20 0.55
GABRA3 P34903 1/20 0.55
GABRA2 P47869 1/20 0.55
GABRB2 P47870 1/20 0.55
GABRA4 P48169 1/20 0.55
GABRE P78334 1/20 0.55
GABRA6 Q16445 1/20 0.55
GABRG1 Q8N1C3 1/20 0.55
GABRG3 Q99928 1/20 0.55
GABRQ Q9UN88 1/20 0.55
TMPRSS4 Q9NRS4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962842 0.89 GSTA1 (0.62) RECQLCA1CA2TMPRSS4LMNA
SCHEMBL11842389 0.87 RECQL (0.77) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL6966672 0.87 CA1 (0.72) CA1CA2TMPRSS4LMNAMAPT
SCHEMBL11843932 0.86 RECQL (0.51) RECQLCA1CA2GABRPGABRD
SCHEMBL9851141 0.85 RECQL (0.74) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL9450719 0.84 CA1 (0.70) RECQLCA1CA2TMPRSS4LMNA
SCHEMBL9248887 0.84 RECQL (0.57) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL29829303 0.83 RECQL (0.71) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL5080596 0.83 RECQL (0.71) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL145897 0.83 GSTA1 (0.75) RECQLLMNAMAPTMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
CN-110746866-A Powder coating with high-temperature yellowing resistance 六安捷通达新材料有限公司 2020-02-04 CN claimed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP claimed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US claimed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US claimed
WO-2023162998-A1 COMPOSITION INCLUDING IODO COMPOUND AND USE FOR SAME 東ソー株式会社 2023-08-31 WO disclosed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP disclosed
CN-110746866-A Powder coating with high-temperature yellowing resistance 六安捷通达新材料有限公司 2020-02-04 CN disclosed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP disclosed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US disclosed
EP-2613819-A1 Lubricious coatings for medical devices Biointeractions Ltd. (GB) 2013-07-17 EP disclosed
WO-2012032283-A1 Lubricious coatings for medical devices BIOINTERACTIONS LTD (GB) 2012-03-15 WO disclosed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US disclosed
US-4564636-A ANTIDEPRESSANTS SYNTHELABO (FR) 1986-01-14 US disclosed
US-4558062-A ANTIDEPRESSANT, ANALYGESIC, ANTIULCER AGENT SYNTHELABO (FR) 1985-12-10 US disclosed
US-4478851-A ANTICONVULSANTS SYNTHELABO (FR) 1984-10-23 US disclosed
US-4400536-A ANTICONVULSANTS; PSCHOLOGICAL DISORDERS; 2-IMINOPHENOLS SYNTHELABO (FR) 1983-08-23 US disclosed