Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884140 | 0.85 | ADORA2A (0.39) | DAPK1TSHRADORA2AALDH1A1SRC | |
| SCHEMBL4061405 | 0.85 | DAPK1 (0.44) | L3MBTL1DAPK1TSHRADORA2AALDH1A1 | |
| SCHEMBL25248533 | 0.85 | L3MBTL1 (0.36) | L3MBTL1NPC1RAB9ASMN1; SMN2DAPK1 | |
| SCHEMBL4062495 | 0.83 | DAPK1 (0.38) | DAPK1MEN1KMT2ATSHRADORA2A | |
| SCHEMBL12880601 | 0.83 | PDE5A (0.37) | L3MBTL1NPC1RAB9ASMN1; SMN2DAPK1 | |
| SCHEMBL934717 | 0.82 | SMN1; SMN2 (0.34) | L3MBTL1NPC1RAB9ASMN1; SMN2DAPK1 | |
| SCHEMBL1573006 | 0.80 | DAPK1 (0.36) | DAPK1TSHRADORA2AALDH1A1BRD4 | |
| SCHEMBL9974797 | 0.76 | P2RX7 (0.31) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21870722 | 0.76 | DGAT1 (0.38) | — | |
| SCHEMBL1222811 | 0.74 | MTAP (0.40) | SMN1; SMN2MEN1KMT2ATSHRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359621-B | Preparation method of intermediates of Li Siwei and Li Siwei and corresponding intermediates of Li Siwei | 上海陶术生物科技股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-118359622-A | Preparation method of Li Siwei intermediate | 上海陶术生物科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118359621-A | Preparation method of intermediates of Li Siwei and Li Siwei and corresponding intermediates of Li Siwei | 上海陶术生物科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| CN-101528749-B | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | IND RES LTD | 2013-07-31 | — | — | CN | disclosed |
| EP-2395005-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | Industrial Research Limited (NZ) | 2011-12-14 | — | — | EP | disclosed |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | BIOCRYST PHARMACEUTICALS, INC. | 2011-06-02 | — | — | US | disclosed |
| EP-2057165-B1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | IND RES LTD (NZ) | 2011-03-16 | — | — | EP | disclosed |
| WO-2008030119-A9 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-09-24 | — | — | WO | disclosed |
| CN-101528749-A | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | IND RES LTD (NZ) | 2009-09-09 | — | — | CN | disclosed |
| EP-2057165-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008030119-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | PNP, TYMP, NTPCR | L3MBTL1 2527/4885NPC1 1242/4885RAB9A 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.