SCHEMBL2743136

SCHEMBL2743136

COc1ccc(C(C)(C)c2ccc(OC(=O)Oc3ccc(C(C)(C)c4ccc(OC(=O)c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.66
TDP1 Q9NUW8 2/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
KMT2A Q03164 8/20 0.52
MEN1 O00255 3/20 0.52
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 2/20 0.50
PKM P14618 2/20 0.50
PARP10 Q53GL7 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
THRB P10828 1/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
CDK5 Q00535 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141568 0.96 MAPT (0.71) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12451790 0.94 MAPT (0.69) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL17792232 0.90 MAPT (0.82) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL13476677 0.90 ALDH1A1 (0.49) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL11617807 0.90 ALDH1A1 (0.49) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12220669 0.90 ALDH1A1 (0.49) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL126322 0.89 MAPT (0.81) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL2743134 0.89 MAPT (0.66) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL16840020 0.89 MAPT (0.66) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL1192185 0.88 MAPT (0.78) MAPTTDP1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170158853-A1 HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 US disclosed
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed
US-20150050587-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed
US-20120045715-A1 SLIPPERY AND CONDUCTIVITY ENHANCED ANTICURL BACK COATING XEROX CORPORATION (US) 2012-02-23 US disclosed
US-20120034555-A1 ANTI-STATIC AND SLIPPERY ANTI-CURL BACK COATING XEROX CORPORATION (US) 2012-02-09 US disclosed
US-20120003575-A1 IMAGING MEMBERS HAVING A CHEMICAL RESISTIVE OVERCOAT LAYER XEROX CORPORATION (US) 2012-01-05 US disclosed
US-20110305981-A1 IMAGING MEMBERS HAVING IMPROVED IMAGING LAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2011-12-15 US disclosed
US-20110256475-A1 IMAGING MEMBERS HAVING A NOVEL SLIPPERY OVERCOAT LAYER XEROX CORPORATION (US) 2011-10-20 US disclosed
US-20110229808-A1 CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE XEROX CORPORATION (US) 2011-09-22 US disclosed
US-20110207038-A1 SLIPPERY SURFACE IMAGING MEMBERS XEROX CORPORATION (US) 2011-08-25 US disclosed
US-20090142569-A1 Optical elements composed of flame-resistant plastics SCHOTT AG (DE) 2009-06-04 US disclosed
US-20080118729-A1 THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-20080119631-A1 THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed