Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333853 | 0.86 | ALDH1A1 (0.48) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL14158221 | 0.75 | LMNA (0.67) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL7007893 | 0.73 | ELANE (0.66) | HPGDALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3583010 | 0.70 | CA1 (0.52) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL2331243 | 0.70 | ALDH1A1 (0.45) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL15984894 | 0.69 | KDM4E (0.60) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL27788739 | 0.68 | ALDH1A1 (0.77) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL14185215 | 0.67 | MAPT (0.48) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL23743855 | 0.67 | KDM4E (0.76) | HPGDALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL14756053 | 0.67 | KDM4E (0.56) | HPGDALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170371-A1 | COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 PHARMACEUTICALS, LLC (US) | 2012-12-13 | — | — | WO | disclosed |