Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158065 | 0.81 | LMNA (0.67) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14158306 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14156914 | 0.81 | LMNA (1.00) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14158350 | 0.80 | LMNA (0.62) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL2332816 | 0.80 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14158069 | 0.78 | LMNA (0.62) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14157081 | 0.78 | LMNA (0.66) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14156919 | 0.75 | HPGD (0.59) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL18550800 | 0.74 | ALDH1A1 (0.70) | LMNAALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14158105 | 0.73 | KMT2A (0.73) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170371-A1 | COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 PHARMACEUTICALS, LLC (US) | 2012-12-13 | — | — | WO | disclosed |