Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384508 | 0.88 | CA1 (0.61) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL28849404 | 0.86 | SMN1; SMN2 (0.72) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL5446847 | 0.84 | TSHR (0.73) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL9011618 | 0.84 | SMN1; SMN2 (0.61) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL15541296 | 0.84 | CA1 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL10759919 | 0.83 | MAPT (0.59) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL9422337 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2RAB9AGAANPC1HPGD | |
| SCHEMBL12124929 | 0.82 | RAB9A (0.69) | CA1CA2CA12ESR1CA7 | |
| SCHEMBL22729216 | 0.82 | CA1 (0.53) | CA1CA2CA12ESR1CA7 | |
| Benzene SCHEMBL27873122 | 0.81 | CA1 (0.76) | CA1CA2CA12ESR1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170554-A1 | N-BIPHENYLMETHYLINDOLE MODULATORS OF PPARG | KAMENECKA THEODORE MARK (US) | 2012-12-13 | — | — | WO | disclosed |