Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615839 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL14157352 | 0.84 | CA1 (0.62) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL10759919 | 0.84 | MAPT (0.59) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL2384508 | 0.83 | CA1 (0.61) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL5446847 | 0.79 | TSHR (0.73) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL3193204 | 0.79 | LMNA (0.67) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL16797151 | 0.78 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL8633952 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL28849404 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL306638 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244526-A1 | Novel hypolipidemic and hypocholesteremic compounds and their preparation and use | Council of Scientific and Industrial Research (IN) | 1987-11-11 | — | — | EP | claimed |
| EP-0447647-B1 | Infrared sensitive silver halide photographic elements | MINNESOTA MINING & MFG (US) | 1996-11-27 | — | — | EP | disclosed |
| US-5232826-A | Comprising 5-arylamine-1,2,3,4-thiatriazole compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0447647-A2 | Infrared sensitive silver halide photographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4737452-A | WITH AROMATIC COMPOUND CONTAINING MERCAPTO AND HYDROZIDE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4731474-A | METAL SUBSTITUTED-A-/3-PENTADECYLPHENOXY/ISOBUTYRATE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 1988-03-15 | — | — | US | disclosed |
| EP-0244526-A1 | Novel hypolipidemic and hypocholesteremic compounds and their preparation and use | Council of Scientific and Industrial Research (IN) | 1987-11-11 | — | — | EP | disclosed |
| EP-0154293-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |