Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943445 | 0.87 | RAB9A (0.88) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL5879030 | 0.87 | RAB9A (0.88) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL4289783 | 0.87 | HPGD (0.71) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL10941324 | 0.87 | NAMPT (0.69) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL1019967 | 0.86 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL21639596 | 0.86 | TSHR (0.77) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL4922844 | 0.86 | MAPT (0.75) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL4112088 | 0.86 | KMT2A (0.75) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9671985 | 0.86 | TSHR (0.77) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL8633952 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6324370-A | — | — | None | — | — | JP | disclosed |
| JP-5224256-A | — | — | None | — | — | JP | disclosed |
| EP-2691402-B1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | ATLANTHERA (FR) | 2019-05-08 | — | — | EP | disclosed |
| CN-102498095-A | Indoline derivatives | TOKYO INST TECH | 2012-06-13 | — | — | CN | disclosed |
| JP-H06324370-A | NONLINEAR OPTICAL MATERIAL | SUMITOMO BAKELITE CO LTD | 1994-11-25 | — | — | JP | disclosed |
| JP-H05224256-A | NONLINEAR OPTICAL MATERIAL | SUMITOMO BAKELITE CO LTD | 1993-09-03 | — | — | JP | disclosed |