Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888900 | 0.83 | GAA (0.46) | CA1CA2CA9CA5ALMNA | |
| SCHEMBL15270664 | 0.82 | TTR (0.41) | CA1CA2CA9CA5AF2 | |
| SCHEMBL364343 | 0.82 | BCAT2 (0.56) | BCAT2CA1CA2CA9CA5A | |
| SCHEMBL3555054 | 0.80 | BCAT2 (0.50) | BCAT2CA1CA2CA9CA5A | |
| Hydrochloric Acid SCHEMBL27374126 | 0.80 | BCAT2 (0.54) | BCAT2CA1CA2CA9CA5A | |
| SCHEMBL2746745 | 0.78 | BCAT2 (0.56) | BCAT2CA1CA2CA9CA5A | |
| SCHEMBL4321077 | 0.77 | BCAT2 (0.59) | BCAT2CA1CA2CA9CA5A | |
| SCHEMBL34748 | 0.75 | BCAT2 (0.62) | BCAT2CA1CA2CA9LMNA | |
| SCHEMBL29838630 | 0.75 | BCAT2 (0.62) | BCAT2CA1CA2CA9LMNA | |
| SCHEMBL30455577 | 0.75 | BCAT2 (0.62) | BCAT2CA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | Rhizen Pharmaceuticals S.A. (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012170867-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |