Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838630 | 1.00 | BCAT2 (0.62) | BCAT2CA1CA2MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL7869876 | 0.98 | BCAT2 (0.61) | BCAT2CA1CA2MMP1MMP2 | |
| Formaldehyde SCHEMBL5182372 | 0.96 | BCAT2 (0.59) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL4321077 | 0.84 | BCAT2 (0.59) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL12492308 | 0.83 | ALOX15 (0.67) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL6631818 | 0.83 | BCAT2 (0.62) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL30455577 | 0.83 | BCAT2 (0.62) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL28208230 | 0.83 | BCAT2 (0.58) | BCAT2CA1CA2MMP1MMP2 | |
| SCHEMBL11348903 | 0.82 | CA1 (0.64) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30444901 | 0.82 | CA1 (0.64) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221460047-U | Waste liquid treatment device for methanesulfonyl benzoic acid production | 河北冀泽生物科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-111886020-B | Peptide macrocycles against acinetobacter baumannii | 豪夫迈·罗氏有限公司 | 2024-04-05 | — | — | CN | claimed |
| EP-4065577-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-10-05 | — | — | EP | claimed |
| WO-2021105091-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-03 | — | — | WO | claimed |
| EP-3551633-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2021-03-31 | — | — | EP | claimed |
| CN-110520410-A | The synthetic method of mesotrione | GHARDA CHEMICALS LTD | 2019-11-29 | — | — | CN | claimed |
| EP-3551634-A1 | SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | claimed |
| EP-3551633-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | claimed |
| WO-2018108230-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2018-06-21 | — | — | WO | claimed |
| US-7781592-B2 | Thione derivative, method for the preparation thereof, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2010-08-24 | — | — | US | claimed |
| US-20080161325-A1 | e.g. N1-[3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]-3-(butylsulfonyl)-N1-(3-ethylbenzyl)-D-alaninamide dihydrochloride; inhibitors of amyloid beta-secretase enzyme; neurodegenerative diseases: Alzheimer's, Parkinson's diseases, Down's syndrome | ELAN PHARMACEUTICALS, INC. | 2008-07-03 | — | — | US | claimed |
| US-20080090875-A1 | Thione Derivative, Method For The Preparation Thereof, And Pharmaceutical Composition Containing The Same | CJC CORPORATION (KR) | 2008-04-17 | — | — | US | claimed |
| WO-2007048064-A2 | AMINO-PYRIMIDINES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2005051941-A1 | THIONE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2005-06-09 | — | — | WO | claimed |
| CN-1127482-C | Sulfuryl diphenyl indole compound and preparation process and use in medicine | INST OF MEDICINE CHINESE ACADE (CN) | 2003-11-12 | — | — | CN | claimed |
| CN-1038584-C | Preparation of methylsulfonylbenzoic acids | BASF AG (DE) | 1998-06-03 | — | — | CN | claimed |
| EP-0594027-B1 | Method for the preparation of methylsulphonylbenzoic acids | BASF AG (DE) | 1996-08-21 | — | — | EP | claimed |
| US-5424481-A | Preparation of methylsulfonylbenzoic acids | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | claimed |
| CN-1090843-A | The preparation method of methyl sulfonylbenzoic acid | BASF AG (DE) | 1994-08-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090875-A1 | Thione Derivative, Method For The Preparation Thereof, And Pharmaceutical Composition Containing The Same | TPMT, TST, CYP3A5 | BCAT2 3661/4885CA1 1852/4885CA2 1649/4885 |
| US-20080161325-A1 | e.g. N1-[3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]-3-(butylsulfonyl)-N1-(3-ethylbenzyl)-D-alaninamide dihydrochloride; inhibitors of amyloid beta-secretase enzyme; neurodegenerative diseases: Alzheimer's, Parkinson's diseases, Down's syndrome | BACE1, APP, BACE2 | BCAT2 211/4885CA1 1011/4885CA2 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.