Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321077 | 0.83 | BCAT2 (0.59) | BCAT2LMNAALDH1A1CA1CA2 | |
| SCHEMBL8966630 | 0.83 | ALDH1A1 (0.50) | BCAT2LMNAALDH1A1ALOX15CA1 | |
| SCHEMBL28176076 | 0.82 | BCAT2 (0.44) | BCAT2LMNAALDH1A1ALOX15CA1 | |
| SCHEMBL27484504 | 0.82 | BCAT2 (0.44) | BCAT2LMNAALDH1A1ALOX15CA1 | |
| SCHEMBL27471073 | 0.81 | BCAT2 (0.42) | BCAT2LMNAALDH1A1ALOX15CA1 | |
| SCHEMBL34748 | 0.81 | BCAT2 (0.62) | BCAT2LMNAALDH1A1ALOX15CA1 | |
| SCHEMBL30455577 | 0.81 | BCAT2 (0.62) | BCAT2LMNAALDH1A1CA1CA2 | |
| SCHEMBL8747678 | 0.81 | ALDH1A1 (0.48) | BCAT2ALDH1A1ALOX15CA1CA2 | |
| SCHEMBL6631818 | 0.81 | BCAT2 (0.62) | BCAT2LMNAALDH1A1CA1CA2 | |
| SCHEMBL29838630 | 0.81 | BCAT2 (0.62) | BCAT2LMNAALDH1A1ALOX15CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190406-C | Preparation method of ortho-alkylated benzoic acid derivative | MERCK PATENT GMBH (DE) | 2005-02-23 | — | — | CN | claimed |
| CN-1127482-C | Sulfuryl diphenyl indole compound and preparation process and use in medicine | INST OF MEDICINE CHINESE ACADE (CN) | 2003-11-12 | — | — | CN | claimed |
| CN-1310700-A | Preparation method of ortho-alkylated benzoic acid derivative | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | CN | claimed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | claimed |
| CN-110520410-A | The synthetic method of mesotrione | GHARDA CHEMICALS LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-106831814-B | A kind of thieno [3,2-d] miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-106831814-A | A kind of thieno [3,2 d] RTIs of miazines HIV 1 and its preparation method and application | 山东大学 | 2017-06-13 | — | — | CN | disclosed |
| CN-102834382-B | The pyrazole derivatives of calcium channel modulators is activated as calcium release | 理森制药股份公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-101805303-B | Substituted hydroxylamine derivatives with anti-inflammatory activity and preparation method and application thereof | UNIV CHINA PHARMA | 2014-06-18 | — | — | CN | disclosed |
| CN-103717581-A | N-(tetrazol-5-yl)- and n-(triazol-5-yl)arylcarboxamides and use thereof as herbicides | BAYER IP GMBH | 2014-04-09 | — | — | CN | disclosed |
| EP-1732904-B1 | DIARYLTRIAZOLES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 | MERCK SHARP & DOHME (US) | 2014-03-19 | — | — | EP | disclosed |
| US-8541457-B2 | Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors | XENON PHARMACEUTICALS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| WO-1996016156-A1 | USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996016155-A1 | BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996016157-A1 | BLEACHING DETERGENT COMPOSITIONS COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |
| EP-0496631-B1 | 2-Cyano-1,3-dione herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-07 | — | — | EP | disclosed |
| EP-0496631-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |