Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157692 | 0.88 | HSD11B1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL14157685 | 0.79 | HSD11B1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL14157708 | 0.79 | HSD11B1 (0.41) | HSD11B1CYP3A4CYP2D6CYP2C9HSD11B2 | |
| SCHEMBL14157702 | 0.74 | MEN1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL14157677 | 0.67 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL15706812 | 0.67 | HSD11B1 (0.52) | HSD11B1HSD11B2 | |
| SCHEMBL14157643 | 0.67 | HSD11B1 (0.52) | HSD11B1HSD11B2 | |
| SCHEMBL31518178 | 0.66 | KIF11 (0.49) | — | |
| SCHEMBL14157575 | 0.65 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| Hydrochloric Acid SCHEMBL30729484 | 0.65 | KIF11 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699560-A2 | 5-CARBAMOYL-ADAMANTAN-2-YL AMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND PREPARATION PROCESS THEREOF | SK Biopharmaceuticals Co., Ltd. (KR) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012169863-A2 | 5-CARBAMOYL-ADAMANTAN-2-YL AMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND PREPARATION PROCESS THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-12-13 | — | — | WO | disclosed |