Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157685 | 0.81 | HSD11B1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL14157692 | 0.80 | HSD11B1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL14157710 | 0.74 | HSD11B1 (0.44) | HSD11B1HSD11B2 | |
| SCHEMBL14157701 | 0.74 | HSD11B1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL18190435 | 0.68 | RAB9A (0.58) | KMT2AKDM4E | |
| SCHEMBL1171646 | 0.66 | KDM4E (0.54) | MEN1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL30092235 | 0.65 | VIP (0.65) | MEN1KMT2ASCN5ASCN9ASCN3A | |
| SCHEMBL3699321 | 0.63 | — | — | |
| SCHEMBL4762388 | 0.63 | HSD11B1 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL2781925 | 0.62 | KDM4E (0.61) | MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699560-A2 | 5-CARBAMOYL-ADAMANTAN-2-YL AMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND PREPARATION PROCESS THEREOF | SK Biopharmaceuticals Co., Ltd. (KR) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012169863-A2 | 5-CARBAMOYL-ADAMANTAN-2-YL AMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND PREPARATION PROCESS THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-12-13 | — | — | WO | disclosed |